| Name | Gender | Meaning | Favorites |
| Sejal | Girl | Full of water, River water | |
| Selvakumaran | Boy | Prosperous | |
| Selvan | Boy | Prosperous | |
| Selvi | Girl | Youthful | |
| Sembaruthi | Girl | Hibiscus, Name of a Beautiful Flower | |
| Semmal | Boy | Perfect | |
| Senbagam | Girl | Name of a Beautiful Flower | |
| Sendhil | Boy | Lord murugan | |
| Sendhilkumaran | Boy | God Murugan | |
| SendhilNathan | Boy | Lord murugan | |
| Sengannan | Boy | Visionary | |
| Senmal | Boy | The best | |
| Senthamarai | Boy | Red lotus | |
| Sesha | Girl | King of Serpents | |
| Sevak | Boy | Servant | |
| Shachin | Boy | Lord Indra | |
| Shailendra | Boy | King of mountains | |
| Shaili | Girl | Style | |
| Shailja | Girl | Another name of Goddess Parvati Shailputri | |
| Shaistakhan | Boy | Polite | |
